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. 2023 May 26;14:3032. doi: 10.1038/s41467-023-38744-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Follow-up time distribution (time from participant’s first to last serology) for samples collected prior (n = 778, yellow) and post (n = 246, purple) vaccination when at least two positive samples were available. Note that participants may have multiple samples prior and post vaccination and may therefore appear in both categories. b Trajectories for all participants (n = 1083) by serological sampling date and according to vaccination status. Colors as in panel (a). c Trajectories of pre-vaccination samples by time from virological confirmation when available (n = 442), along with violin plots of antibody levels in discrete arbitrary categories of time post confirmation (0–149, 150–249, 250–449, 450+ days). d Trajectories post-vaccination by time from latest dose (n = 246). Dashed and dotted lines in panels b–d indicate the upper quantification limit (2500 U/mL, equivalent to 2960 IU/mL) and threshold for positivity (0.8 U/mL, equivalent to 0.95 IU/mL) of the test, respectively. Source data are provided as a Source Data file.