Table 2.
Comparison of cerebral SVD in Meth versus propensity score-matched control group after removing the patients with stimulant use for ADHD.
| Variables | Meth group | PS-matched control group | p |
|---|---|---|---|
| N | 55 | 55 | |
| Age | 55 ± 10 | 55 ± 10 | 0.978 |
| Male (%) | 45 (81.8) | 38 (69.1) | 0.183 |
| Race | 0.006 | ||
| White | 43 (78.2) | 25 (45.5) | |
| Hispanic | 6 (10.9) | 4 (7.3) | |
| Black | 3 (5.5) | 11 (20) | |
| Asian | 2 (3.6) | 10 (18.2) | |
| Other | 1 (1.8) | 5 (9.1) | |
| Hypertension | 36 (65.5) | 31 (56.4) | 0.329 |
| Diabetes | 19 (34.5) | 20 (36.4) | 0.329 |
| Hyperlipidemia | 15 (27.3) | 20 (36.4) | 0.306 |
| Obesity | 10 (18.2) | 13 (23.6) | 0.482 |
| NIHSS | 5 (6) | 4 (6) | 0.245 |
| Cerebral SVD | |||
| WMHs | 3 (3) | 2 (3) | < 0.001 |
| Lacunes | 2 (4) | 1 (2) | 0.032 |
| Microbleeds | 2 (4) | 0 (4) | 0.369 |
| Enlarged perivascular space | 1 (1) | 1 (1) | 0.346 |
| Total burden | 2 (1) | 2 (1) | 0.006 |
| Baseline SBP | 159 ± 31 | 170 ± 39 | 0.083 |
| Baseline DBP | 97 ± 20 | 95 ± 20 | 0.573 |
| SBP at discharge | 130 ± 17 | 133 ± 20 | 0.411 |
| DBP at discharge | 77 ± 13 | 76 ± 13 | 0.703 |
| Reduction in SBP | 27 ± 27 | 40 ± 30 | 0.038 |
| Reduction in DBP | 19 ± 21 | 20 ± 20 | 0.915 |
| Numbers of Antihypertensives | 3 (3) | 2 (3) | 0.790 |
The Meth group in this analysis excluded patients with history of stimulant use for ADHD. Propensity score-matched patients from the Non-Meth group was used as control.
Data are expressed as n (%), mean ± SD, or median (interquartile range, IQR).
ADHD attention deficit hyperactivity disorder, DBP diastolic blood pressure, NIHSS National Institutes of Health Stroke Scale, PS propensity score, SBP systolic blood pressure, WMHs white matter hyperdensities.
Significant are in value [bold].