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. 2023 May 25;13:8494. doi: 10.1038/s41598-023-35788-z

Table 2.

Comparison of cerebral SVD in Meth versus propensity score-matched control group after removing the patients with stimulant use for ADHD.

Variables Meth group PS-matched control group p
N 55 55
Age 55 ± 10 55 ± 10 0.978
Male (%) 45 (81.8) 38 (69.1) 0.183
Race 0.006
 White 43 (78.2) 25 (45.5)
 Hispanic 6 (10.9) 4 (7.3)
 Black 3 (5.5) 11 (20)
 Asian 2 (3.6) 10 (18.2)
 Other 1 (1.8) 5 (9.1)
Hypertension 36 (65.5) 31 (56.4) 0.329
Diabetes 19 (34.5) 20 (36.4) 0.329
Hyperlipidemia 15 (27.3) 20 (36.4) 0.306
Obesity 10 (18.2) 13 (23.6) 0.482
NIHSS 5 (6) 4 (6) 0.245
Cerebral SVD
 WMHs 3 (3) 2 (3)  < 0.001
 Lacunes 2 (4) 1 (2) 0.032
 Microbleeds 2 (4) 0 (4) 0.369
 Enlarged perivascular space 1 (1) 1 (1) 0.346
 Total burden 2 (1) 2 (1) 0.006
Baseline SBP 159 ± 31 170 ± 39 0.083
Baseline DBP 97 ± 20 95 ± 20 0.573
SBP at discharge 130 ± 17 133 ± 20 0.411
DBP at discharge 77 ± 13 76 ± 13 0.703
Reduction in SBP 27 ± 27 40 ± 30 0.038
Reduction in DBP 19 ± 21 20 ± 20 0.915
Numbers of Antihypertensives 3 (3) 2 (3) 0.790

The Meth group in this analysis excluded patients with history of stimulant use for ADHD. Propensity score-matched patients from the Non-Meth group was used as control.

Data are expressed as n (%), mean ± SD, or median (interquartile range, IQR).

ADHD attention deficit hyperactivity disorder, DBP diastolic blood pressure, NIHSS National Institutes of Health Stroke Scale, PS propensity score, SBP systolic blood pressure, WMHs white matter hyperdensities.

Significant are in value [bold].