Figure 2.
Co-expressed gene modules
(A) GSEA of five co-expressed gene modules (M1-M5) in IBD active and remission samples. Circle size represents the number of genes in each module, and colour represents the normalized enrichment score (NES).
(B) GSEA of five co-expressed gene modules (M1-M5) in IBD active and remission samples. Circle size represents the number of genes in each module, and color represents the normalized enrichment score (NES).
(B–D) Top: GO-BP enrichment of genes in M2-M4. The top 10 terms enriched in each module are listed.
Bottom: Protein‒protein interaction (PPI) and correlation networks of genes in each module. Each dot (hub) represents a gene, and lines connecting the genes indicate gene correlations or PPIs (demonstrated by hub colors). The size of the hubs demonstrates the degree of connectivity.