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. 2023 May 6;26(6):106831. doi: 10.1016/j.isci.2023.106831

Figure 4.

Figure 4

Validation of identified potential biomarkers in clinical patients and correlation analysis on their expression levels and the degree of intestine functional recovery

(A) mRNA expression levels of PADI2, FAM162A, AQP8 and SULT1A1 at different timepoints of intestinal injury repair after surgery in patients.

(B) Protein expression levels of PADI2, FAM162A, AQP8 and SULT1A1 at different timepoints of intestinal injury repair after surgery in patients.

(C) AQP8 and SULT1A1 mRNA levels in patients with and without oral dietary intolerance 48 h after surgery and in patients with and without infectious complications 7 days after surgery.

(D) Correlation analysis of the mRNA levels of AQP8 and SULT1A1 at 48 h after surgery and the time of passing flatus and stool. ∗p ≤0.05, ∗∗p ≤0.01, ∗∗∗p ≤0.001, ∗∗∗∗p ≤0.0001, one-way ANOVA with Tukey’s multiple comparisons test. Data are represented as mean ± standard deviation.