Proportion of Treg subsets in patients with lymphedema, post-lymphatic venous anastomosis (LVA), and healthy controls (HCs)
(A) Representative fluorescence-activated cell sorting data of patients with lymphedema and HCs. Comparison of the total proportion of (B) Treg, (C) Treg I, (D) Treg II, and (E) Treg III in CD3+CD4+ T cells among patients with lymphedema, post-LVA, and HC samples.
(F) Correlation between Treg proportion and severity of the extremity lymphedema (EL) index. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Non-parametric, independent, and paired continuous variables were compared using Mann–Whitney U test and Wilcoxon’s rank-sum test, respectively. Data are represented as median +/− interquartile range.