Cytokine production in CD4+ T cells in patients with lymphedema, post-lymphatic venous anastomosis (LVA), and healthy controls (HCs)
The expression of IFN-γ in (A) CD3+CD4+ T cells, (B) CD3+CD4+PD-1+ T cells, and (C) CD3+CD4+PD-1- T cells. The expression of IL-4 in (D) CD3+CD4+ T cells, (E) CD3+CD4+PD-1+ T cells, and (F) CD3+CD4+PD-1- T cells. The expression of IL-17A in (G) CD3+CD4+ T cells, (H) CD3+CD4+PD-1+ T cells, and (I) CD3+CD4+PD-1- T cells. ∗p < 0.05. Non-parametric, independent, and paired continuous variables were compared using Mann–Whitney U test and Wilcoxon’s rank-sum test, respectively. Data are represented as median +/− interquartile range.