Table 8.
Effect of manganese (Mn) and manganese nanoparticles (Mn-NPs) on DNA damage in Pangasianodon hypophthalmus for a period of 96 h.
| Manganese exposure (mg/L) | Comet area | Comet length | Comet DNA | Head area | Head DNA | Head DNA (%) | Tail area | Tail DNA | Tail DNA (%) |
|---|---|---|---|---|---|---|---|---|---|
| Control | 2481 ± 11.45 | 58 ± 1.69 | 462,378 ± 25.85 | 2003 ± 1.63 | 422,358 ± 94.63 | 91.34 ± 4.85 | 478 ± 3.46 | 40,020 ± 59.45 | 8.66 ± 0.39 |
| Mn-110 | 1804 ± 21.32 | 52 ± 1.05 | 217,308 ± 14.13 | 384 ± 11.29 | 57,130 ± 27.63 | 26.29 ± 1.08 | 1420 ± 11.63 | 160,178 ± 7.63 | 73.71 ± 2.17 |
| Mn-111 | 1257 ± 20.06 | 46 ± 1.63 | 213,524 ± 11.12 | 112 ± 1.28 | 16,331 ± 16.85 | 7.65 ± 0.85 | 1145 ± 3.74 | 197,193 ± 6.45 | 92.35 ± 3.19 |
| Mn-112 | 4421 ± 6.18 | 75 ± 2.74 | 807,085 ± 1.63 | 433 ± 5.63 | 80,520 ± 68.39 | 9.98 ± 0.39 | 3988 ± 22.89 | 726,565 ± 28.63 | 90.02 ± 1.07 |
| Mn-113 | 3150 ± 3.56 | 72 ± 3.41 | 386,235 ± 2.39 | 107 ± 1.86 | 5250 ± 2.74 | 1.36 ± 0.17 | 3043 ± 16.59 | 380,985 ± 31.63 | 98.64 ± 5.39 |
| Mn-114 | 495 ± 1.80 | 31 ± 1.06 | 26,184 ± 14.32 | 4 ± 0.21 | 141 ± 2.85 | 0.54 ± 0.11 | 491 ± 3.74 | 26,043 ± 7.63 | 99.46 ± 1.46 |
| Mn-NPs-91 | 670 ± 1.09 | 31 ± 0.63 | 57,092 ± 17.32 | 384 ± 2.95 | 40,941 ± 6.45 | 74.84 ± 2.74 | 317 ± 4.96 | 21,681 ± 6.11 | 25.16 ± 1.37 |
| Mn-NPs-92 | 1513.56 ± 11.63 | 18.67 ± 1.85 | 264,490 ± 2.69 | 522.89 ± 11.63 | 116,321 ± 25.63 | 41.97 ± 1.67 | 1591.78 ± 24.63 | 252,931 ± 18.63 | 41.97 ± 2.08 |
| Mn-NPs-93 | 1594.45 ± 12.71 | 42.91 ± 2.63 | 217,279 ± 3.74 | 514.09 ± 2.85 | 77,819 ± 18.16 | 52.66 ± 2.16 | 1080.36 ± 27.16 | 139,460 ± 32.63 | 47.34 ± 1.06 |
| Mn-NPs-94 | 2236 ± 13.37 | 52 ± 1.11 | 394,598 ± 11.36 | 384 ± 3.48 | 78,590 ± 51.23 | 19.92 ± 1.08 | 1852 ± 2.96 | 316,008 ± 11.28 | 80.08 ± 2.17 |
| Mn-NPs-95 | 820 ± 1.69 | 32 ± 2.46 | 65,662 ± 21.52 | 12 ± 1.08 | 1735 ± 2.74 | 2.64 ± 0.62 | 808 ± 2.96 | 63,927 ± 7.19 | 97.36 ± 3.19 |
Data expressed as mean ± SE (n = 3).