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. 2023 May 12;16:1128545. doi: 10.3389/fnmol.2023.1128545

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Copyright © 2023 Zheng, Harms, Tail, Zhang, Nimmo, Skutella, Kiening, Unterberg, Zweckberger and Younsi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Spinal cord cross-sections of a vehicle animal at 10 × and 40 × magnification stained for Iba1 (A, yellow), TMEM119 (C, red), and Arg1 (E, yellow). (B,D,F) Mean cell density (cells/mm²) of DAPI⁺&Iba1⁺ infiltrating macrophages (B), DAPI⁺&TMEM119⁺ resident microglia (D), and DAPI⁺&Arg1⁺ M2-polarized microglia (F) in the spinal cord 7 days after SCI/sham surgery (n = 6/group; one-way repeated measures ANOVA followed by post-hoc Tukey-HSD-test; ^***p < 0.001; ns = not significant).