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. 2023 May 12;14:1121830. doi: 10.3389/fmicb.2023.1121830

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Copyright © 2023 Lee, Kang, Kim, Park, Lee and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Survival rate of mice inoculated with quercetin and infected with foot-and-mouth disease virus (FMDV). C57BL/6 mice were inoculated with 25 mg/kg (A) or 50 mg/kg (B,C) of either quercetin or ribavirin (positive control) through intraperitoneal (IP) injection. After 16 h (A,B), 1 or 3 days (C), all mice were infected with a 250 LD₅₀ of FMDV (O/VIT/2013) through intraperitoneal (IP) injection. Mice with phosphate-buffered saline (PBS) inoculation served as a negative control. The mice were monitored for 7 days.