Table 1.
Characteristics of seven studies on association of psoriasis with chronic kidney disease and end-stage renal disease.
| Source | Study design and setting | Inclusion criteria | Study population (No. of participants) | HR (95%CI) | |
|---|---|---|---|---|---|
| CKD | ESRD | ||||
| Wan (16) UK | Retrospective cohort THIN | Psoriasis patients aged 18–90 | All psoriasis (143,883) | All psoriasis: 1.05 (1.02–1.07) | All psoriasis: 1.15 (0.84–1.58) |
| Mild psoriasis (136,529) | Mild psoriasis: 0.99 (0.97–1.02) | Mild psoriasis: 0.98 (0.69–1.38) | |||
| Severe psoriasis (7,354) Comparators (689,702) | Severe psoriasis: 1.93 (1.79–2.08) | Severe psoriasis: 4.15 (1.70–10.11) | |||
| Chi (20) Taiwan | Retrospective cohort NHIR | Psoriasis patients | All psoriasis (4,633) | All psoriasis: 1.90 (1.33–2.70) | All psoriasis: 1.14 (0.85–1.53) |
| Mild psoriasis (4,180) | Mild psoriasis: 1.01 (0.85–1.19) | Mild psoriasis: 0.90 (0.64–1.29) | |||
| Severe psoriasis (453) Comparators (922,354) | Severe psoriasis: 1.90 (1.33–2.70) | Severe psoriasis: 2.97 (1.72–5.11) | |||
| Chiu (21) Taiwan | Retrospective cohort HNIR | Psoriasis patients aged over 18 | All psoriasis (4,344) | All psoriasis: 1.47 (1.31–1.64) | All psoriasis: 1.30 (1.01–1.67) |
| Mild psoriasis (397) | Mild psoriasis: 1.47 (1.31–1.66) | Mild psoriasis: 1.27 (0.98–1.65) | |||
| Severe psoriasis (3,947) Comparators (13, 032) | Severe psoriasis: 1.49 (1.04–2.14) | Severe psoriasis: 1.62 (0.72–3.64) | |||
| Parisi (22) UK | Retrospective cohort CPRD | Psoriasis patients aged over 18 | All psoriasis (48,523) | All psoriasis: 1.18 (1.07–1.31) | NA |
| Mild psoriasis (46,439) | |||||
| Severe psoriasis (2,084) Comparators (208,187) | |||||
| Yu (23) Taiwan | Retrospective cohort NHIR | Psoriasis patients | All psoriasis (3,502) Comparators (10,506) | All psoriasis: 3.00 (2.30–3.93) | All psoriasis: 2.03 (1.04–3.96) |
| Lee (15) Korea | Retrospective cohort NHIS | psoriasis patients aged over 20 | All psoriasis (530,307) Comparators (1,590,921) | NA | All psoriasis: 1.58 (1.47–1.68) |
| Liu (14) Taiwan | Retrospective cohort NHIR | Patients aged over 20 | All psoriasis (2,912) Comparators (8,736) | All psoriasis: 2.48 (1.81–3.40) | NA |
CPRD, Clinical practice research datalink; THIN, The health improvement network; NHIR, National health insurance research; NHIS, National health insurance service; CKD, Chronic kidney disease; ESRD, End-stage renal disease; HR, Hazard ratios; CI, Confidence interval; NA, Not available.