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. 2023 May 12;17:1081190. doi: 10.3389/fncel.2023.1081190

FIGURE 1.

FIGURE 1

Free fatty acid (FFA) concentration is reduced in the plasma of SOD1G93A mice. The plasma was obtained from WT or SOD1G93A mice at P60 and P100, and subjected to mass spectrometry for lipid analysis. (A) Kaplan–Meier curve showing the probability of SOD1G93A mice without tremor symptoms (n = 9). (B–D) A heat map showing the z-score of each fatty acid (B), lysophosphatidylcholine (C), and lysophosphatidic acid (D) in the plasma. The rows and columns represent lipids and samples, respectively (E,F). Graph indicating the relative concentration of oleic acid (OA) (E), and linoleic acid (LA) (F) in the plasma. The error bars represent mean ± SEM (n = 4 for each group). *P < 0.05, assessed by one-way ANOVA followed by Tukey–Kramer test for panel (E).