Table 3.
Diabetic nephropathy associated miRs in rat and human uE.
| Rat uE | Human uE | ||
|---|---|---|---|
| S.No | Transcript ID | Fold Change (DN vs. baseline) |
Fold Change (DN vs. DC) |
| 1 | miR-23b-3p | 53.18 | 7.76 |
| 2 | let-7d-5p | 35.24 | 2.35 |
| 3 | let-7c-5p | 63.25 | 10.95 |
| 4 | let-7e-5p | 15.66 | 3.09 |
| 5 | miR-26a-5p | 17.87 | 10.09 |
| 6 | miR-200b-3p | 84.65 | 1.13 |
| 7 | let-7a-5p | 45.59 | 1.69 |
| 8 | miR-200c-3p | 26.79 | 40.43 |
| 9 | miR-182 | 2.27 | 1.1 |
| 10 | let-7b-5p | 71.44 | 32.44 |
| 11 | miR-30a-3p | 9.67 | 1.44 |
| 12 | miR-107 | 4.14 | 1.11 |
| 13 | miR-10a-5p | 2.86 | 1.02 |
| 14 | miR-24-3p | 8.69 | 5.87 |
| 15 | miR-23a-3p | 6.41 | 5.54 |
| 16 | miR-194-5p | 7.34 | 1.54 |
| 17 | miR-378a-3p | 2.21 | 3.13 |
| 18 | miR-200b-5p | 2.3 | 1.08 |
| 19 | miR-92a-3p | 2.14 | 7.45 |
| 20 | miR-29a-3p | 2.28 | 1.11 |
Twenty-eight miRs had significantly higher expression in the pooled uE from rats with diabetic nephropathy, collected between 6th to 8th of diabetes induction (DN), relative to their own baseline (before diabetes induction). The table list 20 miRs among these which were also found in uE from DN patients, relative to subjects with kidney disease. The microarray data was analyzed using TAC 4.0 analysis software.