Table 3.
Multivariable Cox regression analysis of factors contributing to overall mortality of patients presenting an acute VCF
| Covariates | Full model | Final model | ||
|---|---|---|---|---|
| p value | HR (95% CI) | p value | HR (95% CI) | |
| Age | < 0.001 | 1.13 (1.10–1.17) | < 0.001 | 1.13 (1.10–1.16) |
| Gender male | 0.001 | 1.84 (1.29–2.64) | < 0.001 | 1.89 (1.33–2.68) |
| History of cancer | < 0.001 | 2.40 (1.63–3.54) | < 0.001 | 2.19 (1.51–3.18) |
| Chronic steroid treatment | 0.123 | 1.47 (0.90–2.40) | ||
| Previous fracture | 0.108 | 1.35 (0.94–1.93) | ||
| Osteoporosis, diagnosis | 0.800 | 1.05 (0.72–1.54) | ||
| Outpatient geriatric care | 0.585 | 0.87 (0.52–1.45) | ||
| Non-traumatic mechanism | 0.025 | 1.48 (1.05–2.08) | 0.004 | 1.61 (1.16–2.24) |
| Thoracic segment | 0.398 | 1.16 (0.82–1.65) | ||
| Multiple fractures | 0.977 | 0.99 (0.67–1.48) | ||
| Vertebral augmentation | 0.141 | 0.68 (0.41–1.14) | ||
| Co-morbidity hospitalization | 0.001 | 1.83 (1.27–2.64) | < 0.001 | 1.98 (1.40–2.81) |
Statistically significant values are in bold (p<0.05)
HR hazard ratio, CI confidence interval