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. 2023 May 12;14:1143799. doi: 10.3389/fendo.2023.1143799

Figure 1.

Figure 1

Neuropathy Assessment Composite z-Scores. Quantitative sensory testing (QST) parameters are plotted as composite z-scores: z-values of the single tests were clustered to: thermal detection (average values of CDT, WDT, and TSL, demonstrating thermoreceptive Aδ- and C-fiber function), thermal pain (average values of CPT and HPT, representing nociceptive C-fiber function), mechanical detection (average values of VDT and MDT, demonstrating tactile Aβ fiber function), and mechanical pain (average values of MPT, MPS, and PPT, representing nociceptive Aδ and C-fiber function). M-Diet, Mediterranean diet; FMD, fasting-mimicking diet, CDT, cold detection threshold; WDT, warm detection threshold; TSL, thermal sensory limen; CPT, cold pain threshold; HPT, heat pain threshold; PPT, pain pressure threshold; MPT, mechanical pain threshold; MPS, mechanical pain sensitivity; WUR, wind-up ratio; MDT, mechanical detection threshold; VDT, vibration detection threshold. ns, non-significant.