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. 2023 May 11;14:1097070. doi: 10.3389/fneur.2023.1097070

Table 2.

Comparison of clinical characteristics based on IPN grade.

Grade 0 (n = 89) Grade 1 (n = 21) Grade 2 (n = 61) OR 95% CI p
Male, n 64 17 49 1.56 0.79–3.11 0.21
Age, year 65.30 ± 10.18 65.48 ± 10.61 65.61 ± 11.82 1.00 0.98–1.03 0.86
BMI, kg/m2 24.19 ± 3.89 25.35 ± 6.47 25.12 ± 5.08 1.04 0.97–1.10 0.25
Hypertension, n 50 11 41 0.69 0.38–1.24 0.21
Diabetes, n 32 10 21 1.02 0.56–1.85 0.95
Coronary heart disease, n 12 4 8 0.99 0.43–2.27 0.99
LDL-C, mmol/L 2.94 ± 0.77 2.80 ± 1.01 2.85 ± 0.89 0.89 0.63–1.26 0.52
HDL-C, mmol/L 1.31 ± 0.40 1.17 ± 0.32 1.17 ± 0.29 0.33 0.13–0.81 0.02*
TC, mmol/L 4.78 ± 1.15 4.51 ± 1.30 4.62 ± 1.18 0.90 0.70–1.15 0.39
TG, mmol/L 1.39 ± 0.91 1.31 ± 0.43 1.55 ± 1.00 1.20 0.86–1.68 0.28
Statin use history 23 7 19 1.06 0.59–1.88 0.85
Smoking history 47 12 31 0.78 0.42–1.48 0.45

BMI, body mass index; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TC, total cholesterol; and TG, triglyceride; CCA, common carotid artery; ICA, internal carotid artery.