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. 2023 May 25;6(8):e202201853. doi: 10.26508/lsa.202201853

Figure S6. Dysregulated transcripts in alveolospheres stimulated with the fibrosis cocktail.

Figure S6.

Related to Fig 2. (A) Heatmap representation of top 50 differentially expressed genes in FC-stimulated alveolospheres compared with CC stimulation by absolute fold change. P(adj) < 0.05, absolute log2 fold change ≥ 0.7. (B) Heatmap representation of genes related to KEGG pathway hsa04210: apoptosis in FC- or CC-stimulated alveolospheres. (C) Heatmap representation of selected significantly dysregulated senescence-associated secretory phenotype factors from Table 1 in Coppé et al (45) in FC-stimulated alveolospheres compared with CC stimulation by absolute fold change. P(adj) < 0.05, absolute log2 fold change ≥ 0.7. (D) Heatmap representation of genes related to GO_BP:0000723: Telomere maintenance in FC- or CC-stimulated alveolospheres.