Table II.
Study data on risk factors for pediatric hand eczema
| Source | Setting | Study design (yrs) | Age of study participants included (yrs) | No. of total participants | Odds ratio of association between |
||||
|---|---|---|---|---|---|---|---|---|---|
| Female sex and HE (95% CI) | AD and HE (95% CI) | Asthma and HE (95% CI) | Allergic rhinitis and HE (95% CI) | Nickel allergy and HE (95% CI) | |||||
| Grönhagen et al,17 2015 |
Sweden; Birth registry |
Birth cohort (1994-2012) | 0-16 | 2927 | NR | 3.7 (2.0-7.0) (P < .01) |
1.5 (0.8-2.5) (P = .2), 1.2 (0.6-2.1) (P = .6)† |
NR | NR |
| Mortz et al,8 2001 |
Denmark; 40 schools |
Cross-sectional (1995-1997) | 12-16 | 1438 | NR | 5.61 (3.81-8.25) (P < .001) |
1.58 (1.01-2.46) (P < .05) (insignificant after Bonferroni correction)∗ |
NR | NR |
| Röhrl and Stenberg,15 2010 |
Sweden; 11 schools |
Cross-sectional (2000-2004) | 14-24 | 7543 | 2.0 (1.3-3.2) | 4.5 (3.3-6.1) | 1.48 (1.04-2.09) | 1.8 (1.3-2.5) | 1.7 (1.1-2.7) |
| Silverberg et al,16 2021 |
USA, Canada; >20 clinics |
Retrospective (2000-2016) | 0-18 | 1634 | 0.525 (0.497-0.554) (P = .6341) |
0.989 (0.684-1.431) (P = .9550) |
0.622 (0.378-1.023) (P = .0615) |
0.782 (0.511-1.197) (P = .2578) |
0.539 (0.349-0.832) (P = .00525) |
| Wang et al,10 2021 |
Germany; 4 regions |
Cross-sectional (2012-2014) | 15 | 1468 | 1.5 (0.9-2.6) (P = .090) |
1.8 (1.1-2.8) (P = .019) |
NR† | 1.4 (0.8-2.5) (P = .250) |
NR |
AD, Atopic dermatitis; HE, hand eczema; No., number; NR, not reported; Yrs., years.
∗
Also included allergic rhinitis in their calculation.
†
Not reported in multivariable logistic regression analysis.