Table 2.
Comparison of mean rank values and fold change of human gingival fibroblast samples among individual targeted genes.
| Target genes |
Study groups*—Mean ranks |
Kruskal-Wallis -test statistic | p value | |||
|---|---|---|---|---|---|---|
| S-N | S-C | N-N | N-C | |||
| VFGF-A | 5.00 | 2.00 | 8.00 | 11.00 | 10.385 | 0.016* |
| Fold change | 1.00 | 1.07 | 1.55 | 2.60 | ||
| GPX3 | 6.67 | 2.00 | 7.33 | 10.00 | 7.667 | 0.053 |
| Fold change | 1.00 | 0.88 | 1.00 | 1.03 | ||
| SOD2 | 2.00 | 5.00 | 8.00 | 11.00 | 10.385 | 0.016* |
| Fold change | 0.55 | 0.55 | 0.90 | 0.96 | ||
| SOD3 | 6.00 | 2.33 | 7.33 | 10.33 | 7.615 | 0.055 |
| Fold change | 1.00 | 0.82 | 1.01 | 1.14 | ||
| IL-6 | 4.67 | 2.33 | 10.00 | 9.00 | 9.051 | 0.029* |
| Fold change | 0.81 | 0.66 | 12.83 | 12.50 | ||
| IL-8 | 4.33 | 2.67 | 8.00 | 11.00 | 9.667 | 0.022* |
| Fold change | 0.06 | 0.06 | 0.81 | 1.17 | ||
S--N = Smoker without mediation; S-C = Smoker with vitamin C; N-N = Never-smoker without medication; N-C = Never-smoker with vitamin C.
*
Significant p value (P ≤ 0.05).