Table 4.
Multivariate Regression Analysis to Identify Predictors for the Failure of SSM in patients Who Underwent SSM (n = 185).
| Univariate | Multivariate | |||
|---|---|---|---|---|
|
Before backward elimination of non-significant variables |
After backward elimination of non-significant variables |
|||
| OR (95% CI) | OR (95% CI) | OR (95% CI) | P-value | |
| Variable | ||||
| Age (increment per year) | 1.02 (1.00–1.04) | 1.00 (0.97–1.04) | – | – |
| Total bilirubin level (increment per umol/L) | 0.96 (0.91–0.99) | 0.99 (0.96–1.02) | – | – |
| INR | 0.04 (0.01–1.27) | 0.31 (0.00–24.13) | – | – |
| Platelets level (increment per x109/L) | 1.00 (1.00–1.01) | 1.00 (0.99–1.00) | – | – |
| Auto-immune/cholestatic (no/yes) | 0.41 (0.15–1.13) | 0.57 (0.15–2.16) | – | – |
| Other etiology liver disease (no/yes) | 0.22 (0.07–0.78) | 0.40 (0.10–1.67) | – | – |
| Liver cirrhosis (no/yes) | 0.44 (0.21–0.94) | 1.82 (0.48–6.92) | – | – |
| Presence probable CSPH (no/yes)a | 0.24 (0.11–0.55) | 0.55 (0.14–2.23) | – | – |
| Spleen size (increment per cm) | 0.64 (0.53–0.78) | 0.66 (0.49–0.98) | 0.66 (0.52–0.82) | <0.001 |
Abbreviations: CI, confidence interval; cm, centimeter; CSPH, clinically significant portal hypertension; INR, international normalized ratio; n, number; OR, odds ratio; SSM, spleen stiffness measurement.
a
Established if ≥1 of the following items occurred: ascites, varices, hepatic encephalopathy, splenomegaly (corrected for body length and gender), recanalized umbilical vein, portosystemic collaterals, dilated portal veins (splenic vein ≥13 mm or portal vein ≥16 mm), portal hypertensive gastropathy, liver stiffness measurement (LSM) ≥ 25 kPa.