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. 2023 May 4;14:1167873. doi: 10.3389/fphys.2023.1167873

FIGURE 3.

FIGURE 3

Protein and peptide acylating MBOATs. GOAT acylates the peptide hormone ghrelin and prefers octanoyl-CoA as the acyl donor. Hedgehog (PBD: 6RVD) first gets modified with a cholesterol moiety (green) then gets acylated by HHAT with a preference for palmitoyl-CoA. Wnt (PDB: 4F0A) is acylated by PORCN using palmitoleoyl-CoA.