Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 4;14:1167873. doi: 10.3389/fphys.2023.1167873

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Pierce and Hougland.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

cLPCAT3 structural analysis reveals a condition-dependent dimerization state. (A) X-ray crystal structure of cLPCAT3 (PDB ID 7EWT) solved without substrates bound. For comparison to the dimer structure from cryoelectron microscopy, the rotated image on the right is presented in the same orientation as the right (blue) subunit of the dimer in left side of panel (B) Dimeric structure of cLPCAT3 solved by cryoelectron microscopy (PDB ID 7F40) with arachidonoyl CoA (orange) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC, lime green) bound to each monomer. Arrows on the cytosolic top view indicate the lateral/horizontal tunnel for acyl acceptor entry. Figure created using Biorender.