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. 2023 May 12;145(20):11245–11257. doi: 10.1021/jacs.3c01318

Figure 7.

Figure 7

Copper-mediated oxidative ring opening of cyclic amines: reaction scope. Only isolated yields are shown. Reaction conditions: cyclic amine (0.2 mmol), Cu(MeCN)4BF4 (25 mol %), Na2S2O8 (4 equivalents), acetone/H2O (1:9), 24 h. aReaction performed in acetone/H2O (1:1). bReaction performed with 1 equivalent of Cu(MeCN)4BF4.