TABLE 1.
Baseline characteristics of patients on admission.
| Characteristics | C. p (n = 9) | L. p (n = 4) | M. p (n = 5) | χ 2 | P‐value* |
|---|---|---|---|---|---|
| Demographics | |||||
| Female/Male | 6/3 | 4/0 | 3/2 | ||
| Age (years) | 73 (40–80) | 52.5 (33–63) | 42 (14–81) | 4.019 | 0.134 |
| BMI | 20.28 (15.94–27.55) | 27.43 (23.67–29.38) | 23.23 (15.47–26.4) | 5.072 | 0.079 |
| History | |||||
| Cigarette (≥5 years) | 6 | 3 | 1 | ||
| COPD | 6 | 3 | 0 | ||
| HBsAg (−) | 9 | 4 | 5 | ||
| T‐SPOT.TB (−) | 9 | 3 | 5 | ||
| Clinical manifestations | |||||
| Fever ≥ 39°C | 8 | 4 | 1 | ||
| Cough | 9 | 4 | 5 | ||
| Phlegm | 9 | 0 | 1 | ||
| Dyspnoea | 7 | 4 | 2 | ||
| Asthenia | 7 | 3 | 5 | ||
| Shivering | 8 | 4 | 1 | ||
| Headache | 6 | 4 | 1 | ||
| Diarrhoea | 2 | 3 | 0 | ||
| Abdominal distension or pain | 2 | 3 | 0 | ||
| CURB‐65 scores | 1.0 (1.0–5.0) | 2.5 (2.0–4.0) | 0.0 (0.0–2.0) | 4.938 | 0.085 |
| Chest image | |||||
| Unilateral patchy diffusions | 3 | 0 | 3 | ||
| Multiple lobar distributions | 6 | 4 | 2 | ||
| Pleural effusion | 5 | 4 | 0 | ||
| Blood testing (normal range) | |||||
| CD4/CD8 ratio (0.9–3.6) | 2.34 (1.59–6) | 1.87 (1.2–2.78) | 1.8 (1.24–2.36) | 4.339 | 0.114 |
| WBC (3.5–9.5 × 10^9/L) | 8.5 (3.72–15.52) | 11.1 (9.11–12.39) | 5.98 (3.89–6.88) | 6.459 | 0.040 |
| Neutrophils (1.8–6.3 × 10^9/L) | 7.78 (3.52–12.27) | 9.68 (7.23–10.53) | 4.74 (1.91–6.23) | 6.340 | 0.042 |
| Lymphocytes (1.1–3.2 × 10^9/L) | 0.51 (0.12–1.76) | 0.93 (0.69–1.49) | 1.19 (0.70–1.64) | 5.604 | 0.061 |
| CRP (0–5 mg/L) | 188 (116.3–284.53) | 224.4 (211–400.19) | 27.5 (1.34–308.5) | 6.938 | 0.031 |
| PCT (0–0.05 ng/mL) | 1.18 (0.16–3.1) | 2.49 (0.68–6.29) | 0.48 (0.03–0.52) | 6.474 | 0.039 |
| ALT (19–50 U/L) | 84 (28–124) | 116.5 (104–145) | 52 (15–103) | 7.366 | 0.025 |
| AST (15–40 U/L) | 97 (46–264) | 210 (40–346) | 32 (19–153) | 4.316 | 0.116 |
| Albumin (40–55 g/L) | 30 (25–34) | 36.5 (27–43) | 36 (29–45) | 6.153 | 0.046 |
| LDH (120–250 U/L) | 413 (274–695) | 571.5 (469–1897) | 43 (34–664) | 6.474 | 0.039 |
| CK (50–310 U/L) | 216 (22–1092) | 647 (142–3354) | 43 (34–664) | 2.363 | 0.307 |
| Pro‐BNP (0–100 pg/mL) | 664.6 (195.5–4669) | 190.5 (123.3–703.2) | 224.3 (87.3–332.5) | 7.989 | 0.018 |
| Creatinine (57–110 μmol/L) | 66 (46–85) | 94 (82–137) | 65 (51–93) | 6.784 | 0.034 |
| D‐dimer (0–0.5 mg/L) | 1.68 (1.27–3.88) | 3.55 (1.07–5.45) | 1.41 (1.07–12.14) | 0.514 | 0.773 |
| APTT (20.3–32.3 s) | 32.5 (25–52.7) | 34.9 (28.2–36.5) | 28.5 (21.1–42.2) | 1.335 | 0.513 |
| PT (10.7–13 s) | 13.5 (12.5–14.2) | 13.7 (13.4–14.7) | 12.7 (10.6–15.4) | 3.009 | 0.222 |
| BALF testing | |||||
| Neutrophils (%) | 72 (38–93) | 62 (20–76) | 71 (16–85) | 1.400 | 0.497 |
| Lymphocytes (%) | 20 (2–62) | 36 (23–76) | 29 (15–84) | 2.083 | 0.353 |