Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 May 26;21:168. doi: 10.1186/s12951-023-01906-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — Characterization of MF NPs and CH6-MF NPs. (A) HRTEM image of synthesized MnFe₂O₄ NPs. The NPs exhibited a large number of surface defects with a twisted lattice, dislocations and distortions (inset: TEM image of synthesized MnFe₂O₄ nanoparticles, scale bar = 100 nm). (B) XRD spectrum of synthesized MnFe₂O₄ nanoparticles, MF NPs, and tetragonal standard MnFe₂O₄. (C) N₂ adsorption/desorption isotherms of synthesized MnFe₂O₄ NPs. (D) Pore size distribution of synthesized MnFe₂O₄ NPs with abundant surface defects. (E) UV–vis spectra of synthesized MnFe₂O₄ NPs and MF NPs. (F) FTIR spectra of MF NPs and CH6-MF NPs. (G) UV–vis spectra of MF NPs and CH6-MF NPs from 200 to 300 nm. (H) Agarose gel electrophoresis (110 V, 5 min) of NP-siRNA complexes at different weight ratios. (I) Zeta potential variations of synthesized MnFe₂O₄ NPs, CH6-MF NPs and CH6-MF NPs/siRNA. (J) siRNA serum stability of naked siRNA, MF NPs/siRNA and CH6-MF NPs/siRNA complexes(NP:siRNA weight ratio of 10:1) incubated with fetal bovine serum(50% final concentration) at 37 °C for different times. Data were analysed by Student’s t test and one-way ANOVA. The outcomes are presented as the mean ± Sd. ns = statistically nonsignificant, *P < 0.05, **P < 0.01, and ***P < 0.001; n = 3