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p53 mutants containing C-terminal K-to-R substitutions show higher transcriptional activity than does WT p53. Saos-2 cells were cotransfected by electroporation with expression plasmids for WT p53 or K-to-R mutants and the pG13-Luc reporter plasmid. Each point is the mean of four independent transfections, with error bars representing 1 standard deviation.
