Figure 1.
(a) Visible colonic lesions in the different groups of TNBS-induced rat colitis. Representative images of colonic inflammation in the experimental groups: (b) Ctrl (absolute control, no treatment); (c) EtOH (50% ethanol, the solvent of TNBS); (d) TNBS (2,4,6-trinitrobenzenesulfonic acid enema); (e) TNBS + LR (TNBS + 18.75 µM/kg/day Lawesson’s reagent); (f) TNBS + CMC (TNBS + 0.5% carboxymethylcellulose, the vehicle of Lawesson’s reagent). Results are shown as mean ± S.E.M.; n = 6–12/group; one-way ANOVA, Holm–Sidak post hoc test, and && p < 0.001 Ctrl vs. EtOH; ## p < 0.001 Ctrl vs. TNBS; ** p < 0.001 TNBS vs. TNBS + LR.