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. 2023 Apr 28;12(5):1028. doi: 10.3390/antiox12051028

Table 2.

Bioactive compounds obtained from CBS using different extraction methods, all data, expressed on a dry weight basis.

Extraction Method Value References
Antioxidant activity Ethanol, methanol–acetone, water, UAE, MAE 2.5–218 µM TE/g CBS [28,30,39,48]
Total phenolic content Ethanol, methanol–acetone, water, methanol, acetone, UAE, SWE, PEF, MAE 5.8–154.4 mg GAE/g CBS [30,32,40,61,63,79,80]
Total flavonoid content Ethanol, acetone, methanol, PEF 1.6–43.9 mg CE/g CBS [39,40]
Total tannin content Ethanol, acetone, methanol, PEF 0.8–25.3 mg CE/g CBS [39,40]
Total dietary fibre Ethanol, acetone, methanol 51.8–56.7 g/100 g CBS [32]
Soluble dietary fibre Ethanol, acetone, methanol 14.5–16.2 g/100 g CBS [32]
Insoluble dietary fibre Ethanol, acetone, methanol 35.6–42.1 g/100 g CBS [32]
Theobromine Ethanol, methanol, water, UAE, SWE, PEF, MAE 1.3–11.6 mg/g CBS [28,30,40,42,79,80,83]
Caffeine UAE, SWE, PEF, MAE 0.1–4.2 mg/g CBS [30,40,42,50]
Theophylline SWE Traces-0.2 mg/g CBS [42]
Catechin Ethanol, water, methanol, PHWE 0.2–6.1 mg/g CBS [49,61,83,85]
Epicatechin Ethanol, methanol, water, PEF, MAE, PHWE 0.3–17.7 mg/g CBS [28,40,48,61,83]
Procyanidin B1 Ethanol, water 0.5–0.8 mg/g CBS [48]
Procyanidin B2 Ethanol, water 0.2–0.9 mg/g CBS [48]
Protocatechuic acid Ethanol, water, MAE 0.9–2.1 mg/g CBS [28,48]
Caffeic acid Ethanol, water, methanol, MAE Traces-0.9 mg/g CBS [28,61]
Ferulic acid MAE 0.3–0.5 mg/g CBS [28]

MAE: Microwave-assisted extraction; PEF: Pulsed-electric-field-assisted extraction; PHWE: Pressurized hot water extraction; SWE: Subcritical water extraction; UAE: Ultrasound-assisted extraction.