Table 2.
Ingenuity-pathway-analysis-based transcriptome profiles of the 6 h-stored hBM-MSCs.
| Entrez Gene Name | Symbol | Entrez Gene ID a | Location | Fold Change b |
|---|---|---|---|---|
| ATP binding cassette subfamily B member 7 | ABCB7 | 22 | Cytoplasm | 1.637 |
| argonaute RISC component 1 | AGO1 | 26,523 | Cytoplasm | −1.542 |
| aldo-keto reductase family 1 member A1 | AKR1A1 | 10,327 | Cytoplasm | 1.512 |
| AKT serine/threonine kinase 3 | AKT3 | 10,000 | Cytoplasm | −2.379 |
| alkB homolog 1, histone H2A dioxygenase | ALKBH1 | 8846 | Cytoplasm | −1.503 |
| aryl hydrocarbon receptor nuclear translocator | ARNT | 405 | Nucleus | 1.715 |
| activating transcription factor 3 | ATF3 | 467 | Nucleus | 2.88 |
| BCL2 associated X, apoptosis regulator | BAX | 581 | Cytoplasm | −1.946 |
| BCL2 apoptosis regulator | BCL2 | 596 | Cytoplasm | 1.534 |
| BCL2 like 11 | BCL2L11 | 10,018 | Cytoplasm | −1.579 |
| 3′(2′), 5′-bisphosphate nucleotidase 1 | BPNT1 | 10,380 | Nucleus | 1.564 |
| bromodomain containing 3 | BRD3 | 8019 | Nucleus | 1.855 |
| calpain 3 | CAPN3 | 825 | Cytoplasm | −1.974 |
| cyclin dependent kinase 12 | CDK12 | 51,755 | Nucleus | 1.925 |
| caseinolytic mitochondrial matrix peptidase chaperone subunit B | CLPB | 81,570 | Nucleus | −1.785 |
| Clusterin | CLU | 1191 | Cytoplasm | −1.768 |
| cAMP responsive element binding protein 1 | CREB1 | 1385 | Nucleus | −2.252 |
| cathepsin D | CTSD | 1509 | Cytoplasm | 1.527 |
| Cytoglobin | CYGB | 114,757 | Cytoplasm | 2.368 |
| cytochrome P450 family 2 subfamily E member 1 | CYP2E1 | 1571 | Cytoplasm | 2.095 |
| Dystonin | DST | 667 | Plasma Membrane | 2.126 |
| early growth response 1 | EGR1 | 1958 | Nucleus | 1.915 |
| elongation factor for RNA polymerase II 3 | ELL3 | 80,237 | Nucleus | 1.749 |
| coagulation factor II thrombin receptor like 2 | F2RL2 | 2151 | Plasma Membrane | −1.714 |
| fibroblast growth factor receptor 2 | FGFR2 | 2263 | Plasma Membrane | −1.859 |
| fragile X messenger ribonucleoprotein 1 | FMR1 | 2332 | Cytoplasm | −1.569 |
| fibronectin 1 | FN1 | 2335 | Extracellular Space | −1.951 |
| hes family bHLH transcription factor 1 | HES1 | 3280 | Nucleus | 8.134 |
| high mobility group box 1 | HMGB1 | 3146 | Nucleus | −1.903 |
| interleukin 11 | IL11 | 3589 | Extracellular Space | 1.596 |
| interleukin 6 | IL6 | 3569 | Extracellular Space | 1.784 |
| insulin receptor | INSR | 3643 | Plasma Membrane | 1.561 |
| integrin subunit beta 1 | ITGB1 | 3688 | Plasma Membrane | −2.31 |
| inositol 1,4,5-trisphosphate receptor type 1 | ITPR1 | 3708 | Cytoplasm | 1.775 |
| jade family PHD finger 1 | JADE1 | 79,960 | Nucleus | −1.76 |
| Jun proto-oncogene, AP-1 transcription factor subunit | JUN | 3725 | Nucleus | 2.212 |
| potassium calcium-activated channel subfamily M alpha 1 | KCNMA1 | 3778 | Plasma Membrane | −1.726 |
| lysine demethylase 6A | KDM6A | 7403 | Nucleus | −1.511 |
| KLF transcription factor 2 | KLF2 | 10,365 | Nucleus | 2.261 |
| KLF transcription factor 9 | KLF9 | 687 | Nucleus | 1.803 |
| low density lipoprotein receptor | LDLR | 3949 | Plasma Membrane | −1.783 |
| leptin receptor | LEPR | 3953 | Plasma Membrane | −1.575 |
| lamin B1 | LMNB1 | 4001 | Nucleus | −1.862 |
| LDL receptor related protein associated protein 1 | LRPAP1 | 4043 | Plasma Membrane | −2.12 |
| LYN proto-oncogene, Src family tyrosine kinase | LYN | 4067 | Cytoplasm | −1.541 |
| MAPK activated protein kinase 2 | MAPKAPK2 | 9261 | Nucleus | 1.848 |
| matrix metallopeptidase 14 | MMP14 | 4323 | Extracellular Space | −1.874 |
| N-acylethanolamine acid amidase | NAAA | 27,163 | Cytoplasm | −2.184 |
| nuclear receptor coactivator 3 | NCOA3 | 8202 | Nucleus | −1.572 |
| NFE2 like bZIP transcription factor 2 | NFE2L2 | 4780 | Nucleus | −1.823 |
| nuclear receptor subfamily 3 group C member 1 | NR3C1 | 2908 | Nucleus | 2.214 |
| nuclear receptor subfamily 4 group A member 1 | NR4A1 | 3164 | Nucleus | 1.808 |
| nuclear receptor subfamily 4 group A member 2 | NR4A2 | 4929 | Nucleus | 4.047 |
| neuregulin 1 | NRG1 | 3084 | Plasma Membrane | −1.913 |
| O-linked N-acetylglucosamine (GlcNAc) transferase | OGT | 8473 | Cytoplasm | −2.058 |
| programmed cell death 4 | PDCD4 | 27,250 | Nucleus | 1.554 |
| platelet and endothelial cell adhesion molecule 1 | PECAM1 | 5175 | Plasma Membrane | 1.602 |
| phosphoinositide kinase, FYVE-type zinc finger containing | PIKFYVE | 200,576 | Cytoplasm | −1.529 |
| phospholipase A2 activating protein | PLAA | 9373 | Cytoplasm | −1.507 |
| peroxisome proliferator activated receptor alpha | PPARA | 5465 | Nucleus | 1.646 |
| peroxiredoxin 2 | PRDX2 | 7001 | Cytoplasm | −2.276 |
| perforin 1 | PRF1 | 5551 | Cytoplasm | 1.668 |
| protein kinase AMP-activated catalytic subunit alpha 1 | PRKAA1 | 5562 | Cytoplasm | −2.252 |
| prostaglandin E receptor 3 | PTGER3 | 5733 | Plasma Membrane | −1.539 |
| protein tyrosine phosphatase receptor type B | PTPRB | 5787 | Plasma Membrane | 2.444 |
| RAB7A, member RAS oncogene family | RAB7A | 7879 | Cytoplasm | 1.801 |
| Rac family small GTPase 1 | RAC1 | 5879 | Plasma Membrane | −2.019 |
| RUNX family transcription factor 1 | RUNX1 | 861 | Nucleus | −1.616 |
| sphingosine-1-phosphate receptor 2 | S1PR2 | 9294 | Plasma Membrane | −1.73 |
| Stratifin | SFN | 2810 | Cytoplasm | 1.7 |
| SNF2 histone linker PHD RING helicase | SHPRH | 257,218 | Nucleus | −1.812 |
| solute carrier family 37 member 4 | SLC37A4 | 2542 | Cytoplasm | 3.046 |
| solute carrier family 7 member 11 | SLC7A11 | 23,657 | Plasma Membrane | 1.721 |
| SMAD family member 4 | SMAD4 | 4089 | Nucleus | −2.153 |
| sphingomyelin phosphodiesterase 1 | SMPD1 | 6609 | Cytoplasm | −1.834 |
| suppressor of cytokine signaling 3 | SOCS3 | 9021 | Cytoplasm | 1.628 |
| superoxide dismutase 2 | SOD2 | 6648 | Cytoplasm | −2.242 |
| striated muscle enriched protein kinase | SPEG | 10,290 | Nucleus | 1.771 |
| Sarcospan | SSPN | 8082 | Plasma Membrane | 1.575 |
| signal transducer and activator of transcription 6 | STAT6 | 6778 | Nucleus | −1.571 |
| stanniocalcin 1 | STC1 | 6781 | Extracellular Space | −1.567 |
| SUZ12 polycomb repressive complex 2 subunit | SUZ12 | 23,512 | Nucleus | −2.001 |
| T-box transcription factor 3 | TBX3 | 6926 | Nucleus | −1.533 |
| transcription factor 3 | TCF3 | 6929 | Nucleus | 1.81 |
| transforming growth factor beta receptor 2 | TGFBR2 | 7048 | Plasma Membrane | −1.822 |
| TIA1 cytotoxic granule associated RNA binding protein | TIA1 | 7072 | Nucleus | −2.369 |
| transient receptor potential cation channel subfamily C member 1 | TRPC1 | 7220 | Plasma Membrane | −1.812 |
| TSC22 domain family member 3 | TSC22D3 | 1831 | Nucleus | 2.134 |
| twist family bHLH transcription factor 2 | TWIST2 | 117,581 | Nucleus | 1.652 |
| twinkle mtDNA helicase | TWNK | 56,652 | Cytoplasm | −2.459 |
| thioredoxin interacting protein | TXNIP | 10,628 | Cytoplasm | −1.567 |
| TYRO3 protein tyrosine kinase | TYRO3 | 7301 | Plasma Membrane | 1.905 |
| ubiquitin specific peptidase 16 | USP16 | 10,600 | Cytoplasm | −1.764 |
| zinc finger and BTB domain containing 14 | ZBTB14 | 7541 | Nucleus | −1.55 |
| ZFP36 ring finger protein | ZFP36 | 7538 | Nucleus | 1.827 |
a The Entrez gene ID is the unique integer identifier for humans; b normalized signal fold change in the 6 h-stored group to the corresponding signal of the control group.