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Shikonin augmented the antibacterial activity of gentamicin: (A) the well containing 10 mg gentamicin demonstrated a growth-inhibition zone against E. coli of 28 mm, (B) the well containing 10 mg shikonin showed a growth-inhibition zone against E. coli of 15 mm, (C) the well containing 5 mg gentamicin and 5 mg shikonin had a 33 mm inhibitory zone against E. coli.
