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Effect of Paigen-type diet and osthole administration in cardiac KHK expression measured by immunohistochemistry after 30 days follow-up. Black arrows point to cardiac endothelial cells positive for KHK. White arrows represent three endothelial cells in a venule. Data are presented as the mean ± standard deviation and were analyzed by one-way ANOVA. Analysis post hoc was performed using Tukey’s multiple comparison test. Statistical differences were established as **** p ≤ 0.0001.
