| ICIs | immune checkpoint inhibitors |
| MSI-H | microsatellite instability-high |
| FDA | The United States Food and Drug Administration |
| NSCLC | non-small cell lung cancer |
| EGFR-TKI | epidermal growth factor receptor-tyrosine kinase inhibitor |
| Tregs | regulatory T cells |
| LAG-3 | lymphocyte activation gene-3 |
| TIM-3 | T cell immunoglobulin and mucin domain-3 |
| Tight | T cell immunoglobulin and ITIM domain |
| PFS | progression-free survival |
| TME | tumor microenvironment |
| VEGF | vascular endothelial growth factor |
| HCC | hepatocellular carcinoma |
| OS | overall survival |
| mPFS | median PFS |
| mOS | median OS |
| RCC | renal cell carcinoma |
| mCRC | metastatic colorectal carcinoma |
| ORR | objective response rate |
| EGFR | epidermal growth factor receptor |
| HER2 | human epidermal growth factor receptor 2 |
| DOR | duration of response |
| T-DM1 | trastuzumab emtansine |
| ADCs | antibody-drug conjugates |
| PARP | poly ADP-ribose polymerase |
| HRR | homologous recombination repair |
| HRD | homologous recombination deficiency |
| TMB | tumor mutation burden |
| TNBC | triple-negative breast cancer |
| TPS | tumor proportion score |
| AR | androgen receptor |
| ER | estrogen receptor |
| PR | progesterone receptor |
| HR+/HER2− | hormone receptor positive/HER2 negative |
| CDKs | cyclin-dependent kinases |
| ALK | anaplastic lymphoma kinase |
| CAR-T | Chimeric antigen receptor T cell |
| NK | Natural killer |