Table 3.
Asthma Phenotypes | Platelet 5-HT Concentration (nmol/mg Protein) |
Platelet MAO-B Activity (nmol/mg of Protein Per Hour) |
||
---|---|---|---|---|
T2-high (N = 94) T2-low (N = 26) |
0.79 (0.62; 1.09) |
p = 0.73; U = 1168.00 FC = 0.95 |
42.98 (35.30; 58.48) |
p = 0.60; U = 1140.00 FC = 0.96 |
0.91 (0.60; 1.09) | 44.27 (31.81; 58.98) | |||
Non-allergic (N = 42) Allergic (N = 78) |
0.85 (0.62; 1.18) |
p = 0.77; U = 1585.00 FC = 1.02 |
37.79 (31.67; 57.17) |
p = 0.047; U = 1278.00 FC = 1.13 |
0.77 (0.62; 1.08) | 44.87 (36.73; 58.60) | |||
Non-eosinophilic (N = 73) Eosinophilic (N = 47) |
0.81 (0.62; 1.05) |
p = 0.39; U = 1554.00 FC = 1.09 |
41.91 (33.63; 59.14) |
p = 0.57; U = 1609.00 FC = 1.03 |
0.86 (0.64; 1.19) | 44.61 (35.32; 57.49) | |||
Non-AERD (N = 111) AERD (N = 9) |
0.81 (0.62; 1.08) |
p = 0.42; U = 413.50 FC = 1.05 |
43.15 (34.07; 58.60) |
p = 0.71; U = 457.00 FC = 0.95 |
0.82 (0.69; 1.31) | 36.50 (33.93; 57.21) |
Platelet 5-HT concentration and MAO-B activity are presented as median with 25th (Q1) and 75th (Q3) percentiles and compared in patients with different asthma phenotypes using the Mann-Whitney test; AERD = aspirin-exacerbated respiratory disease. FC = fold change.