Table 1.
Baseline patient characteristics.
| COVpos n = 47 |
COVneg n = 36 |
Mann–Whitney U or Chi-Squared Test | |
|---|---|---|---|
| Demographics | |||
| Age (years) 1 | 70 [55; 78] | 72.5 [58; 80.8] | 0.380 |
| Female (% per group) | 31.9 | 41.7 | 0.362 |
| Men (% per group) | 68.1 | 58.3 | 0.362 |
| BMI (kg/m^2) 1 | 26.5 [24.7; 30.4] | 25 [23.1; 28.1] | 0.140 |
| Patients with severe illness | 21 | 8 | 0.035 |
| Deceased patients | 7 | 0 | 0.010 |
| Pre-existing conditions | |||
| Coronary artery disease (% per group) | 14.9 | 30.6 | 0.088 |
| Peripheral artery disease (% per group) | 4.3 | 30.6 | 0.001 |
| Arterial hypertension (% per group) | 63.8 | 66.7 | 0.789 |
| Diabetes (% per group) | 27.7 | 22.2 | 0.575 |
| Dyslipidemia (% per group) | 29.8 | 27.8 | 0.842 |
| COPD or asthma bronchial (% per group) | 6.4 | 36.1 | 0.001 |
| Concomitant medication | |||
| Acetylsalicylic acid (% per group) | 38.3 | 30.6 | 0.466 |
| Clopidogrel (% per group) | 4.3 | 0 | 0.213 |
| Prophylactic-dose anticoagulation (% per group) | 25.5 | 58.3 | 0.003 |
| Intermediate-dose anticoagulation (% per group) | 27.7 | 8.3 | 0.028 |
| Therapeutic-dose anticoagulation (% per group) | 46.8 | 33.3 | 0.219 |
| Statin (% per group) | 25.5 | 25.0 | 0.956 |
| ACE blocker (% per group) | 25.5 | 36.1 | 0.301 |
| Angiotensin II receptor blocker (% per group) | 21.3 | 16.7 | 0.600 |
| Beta blocker (% per group) | 27.7 | 47.2 | 0.068 |
| Aldosterone antagonist (% per group) | 6.4 | 13.9 | 0.254 |
| Diuretic (% per group) | 38.3 | 47.2 | 0.417 |
| Oral glucocorticoid (% per group) | 55.3 | 19.4 | 0.001 |
| Inhalative bronchodilator (% per group) | 85.1 | 58.3 | 0.006 |
| Coagulation markers | |||
| tPA (ng/mL) 1 | 11.1 [7; 23.8] | 7.3 [4.9; 10.6] | 0.004 |
| TAT (ng/mL) 1 | 4.9 [3.7; 7.8] | 3.4 [2.5; 4.5] | 0.0001 |
| TF protein (ng/l) 1 | 343.3 [119.5; 647.7] | 133.0 [84.2; 197.1] | 0.004 |
| TF activity (pM) 1 | 356.6 [117.3; 647.7] | 117.6 [83.1; 167.3] | 0.001 |
| TFPI (ng/mL) 1 | 172.0 [130.6; 256.0] | 105.7 [67.1; 160.6] | 0.006 |
| vWF (mlU/mL) 1 | 5100.8 [2953.3; 5472.6] | 2903.9 [1897.2; 4393.7] | 0.021 |
| Beta-defensin 1 1 | 1.2 [0.9; 1.7] | 1.5 [0.8; 2.4] | 0.693 |
1 median values with quartiles.