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Endogenous BCL6 is associated with replication foci in lymphoid Karpas 422 cells. Images show simultaneous visualization at the ultrastructural level of BCL6 and BrdU-containing DNA following a 15-min pulse. The arrow points to a cluster of BCL6 (polyclonal antibody N3 and 5-nm gold particles) located among the BrdU-containing DNA molecules (monoclonal anti-BrdU antibodies and 10-nm gold particles). c, cytoplasm; ch, perinuclear condensed chromatin. Bar, 0.5 μm.
