Table 4.
Late * toxicities (evaluable in 12 cases).
| Adverse Effects | None (n) |
Grades 1–2 (n) |
Grade 3 (n) |
Grade 4 (n) |
|---|---|---|---|---|
| Osteoradionecrosis | 8 | 3 | 1 | 0 |
| Soft tissue necrosis | 4 | 6 | 2 | 0 |
| Hemorrhage | 11 | 0 | 0 | 1 |
| Cranial neuropathy | 9 | 1 | 2 | 0 |
| Dysphagia | 6 | 5 | 1 | 0 |
| Pain | 2 | 8 | 2 | 0 |
| Skin ulceration | 7 | 1 | 4 | 0 |
| Alopecia | 12 | 0 | 0 | 0 |
| Impaired hearing | 11 | 1 | 0 | 0 |
| Otitis | 9 | 2 | 1 | 0 |
| Xerostomia | 8 | 4 | 0 | 0 |
| Edema (H&N) | 10 | 2 | 0 | 0 |
| Trismus | 8 | 3 | 1 | 0 |
| Infection | 4 | 7 | 1 | 0 |
H&N, head and neck. * Toxicities that developed beyond 3 months after the last fraction of BNCT.