Figure 1.

Individual variability in LRR and outcome measures after rodent TBI, which can be translated to human mTBI. Data is hypothetical. Increases in loss of righting reflex (LRR) are directly correlated with increases in symptom severity. Data points on the trend line represent individual rodents, with less and more symptomatic rodents in blue and red, respectively. Symptom severity in these rodents is graphically portrayed in the insets in the form of rotarod performance (motor impairments), Morris water maze performance (cognitive and memory deficits), neuronal degeneration and blood-based biomarkers (pathology), and corticosterone (CORT) levels (physiology). Image created with BioRender.com.