Table 2.
SNPs of TMEM175 in diseases.
| SNP/Mutation | Genomic Position (bp) | Reference Allele | Alternate Allele | Disease | References |
|---|---|---|---|---|---|
| rs34311866 | Chr.4:951947 | T | C | PD | [35] |
| rs34311866 | Chr.4:951947 | T | C | RBD | [72,102] |
| rs34884217 | Chr.4:950422 | A | C | PD | [35] |
| rs2290402 | Chr.4:931518 | T | C | Type 2 diabetes | [105] |
| rs2290405 | Chr.4:953186 | G | A, C | Breast cancer | [106] |
| rs2290405 | Chr.4:953186 | G | A, C | Systemic sclerosis | [107] |
| rs6599388 | Chr.4:945299 | C | T | Lewy body dementia | [108] |
| c.A526G | Chr.4:949608 | A | G | Early-onset PD | [103] |
| c.C547T | Chr.4:947062 | C | T | Late-onset PD | [104] |
| p.Arg377His | - | - | - | Short QT Syndrome | [109] |
Abbreviations: PD, Parkinson’s disease; RBD, rapid eye movement sleep behavior disorder.