Figure 2.

(a) Three representative cases of BM imaging datasets tested using the transferred neural network. Anatomical MR images revealed the development of multifocal lesions, many of which retained a partially or fully intact BTB. Green arrows, yellow arrows, and red arrowheads correspond to those enhanced, minimally enhanced, and non-enhanced lesions, respectively. Corresponding ETM and CNN maps of permeability parameter Ktrans display marked differential permeability between lesions with good agreement. (b) Representative MR images of Case 3 and corresponding DCE SI changes over time for four lesions. The black dashed line represents the contrast agent arrival. Lesions 1 and 2 displayed high-level permeability and moderate-level permeability, respectively. Lesions 3 and 4 were minimally permeable and impermeable, respectively.