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. Author manuscript; available in PMC: 2024 Mar 30.
Published in final edited form as: Cell. 2023 Mar 22;186(7):1382–1397.e21. doi: 10.1016/j.cell.2023.02.022

Figure 6. Dopaminergic activity is influenced by dietary proteins and CCHa1. Different sensory modalities can be gated independently.

Figure 6.

(A) (I) Arousability from sleep on regular food (gray) vs peptone-supplemented food (blue), in controls (PAMMB441B>GFP-RNAi and UAS-CCHa1R-RNAi) and in flies with the CCHa1 receptor depleted from PAMMB441B neurons (PAMMB441B >CCHa1-RNAi, purple outline). (B) Activity of PAMMB441B neurons on regular vs protein-supplemented food. Purple outline, flies in which the CCHa1 receptor is depleted from PAMMB441B neurons. (C) Activity of PAMMB441B neurons on regular vs protein-supplemented food, with or without exposure to mechanical vibrations. (D) Arousability from sleep in response to heat. (E) Arousability by heat on regular vs peptone-supplemented food. (F) Arousability by heat in controls vs animals with the CCHa1 receptor depleted from PAMMB441B neurons. (G) Schematic. Error bars, mean and S.E.M. Genotypes, sample sizes, and statistical analyses, Table S3. See also Figure S6.