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. 2023 May 17;30(5):5116–5134. doi: 10.3390/curroncol30050387

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Circulating Treg proportions do not significantly change long-term following surgery. Matched dot plots demonstrating no significant differences in total Tregs or the three Treg fractions at 6 months (n = 6), 12 months (n = 7) or 18 months (n = 4) in patients with available data. Dots connected by lines indicate individual patients. Fr I (resting Treg): CD45RA+FoxP3+CD25+, Fr II (activated Treg): CD45RA-FoxP3++CD25+, Fr III (mixture of Treg and non-Treg): CD45RA-FoxP3+CD25+. Significance determined via paired Student’s t tests. ns: non-significant. Data are from 10 individual patients.