Table 3.
The laboratory data before and after 3 days of antibiotic treatment in E. coli and non-E. coli urinary tract infection.
| Urinary Tract Infection | p Value | Logistic Regression | |||||
|---|---|---|---|---|---|---|---|
|
E. coli (n = 69) |
Non-E. coli
(n = 17) |
OR (95% C.I.) |
p Value | ||||
| Blood laboratory | * p value | * p value | |||||
| WBC (1000/μL) | <0.001 | 0.007 | |||||
| Before | 14.96 ± 4.50 | 13.09 ± 5.83 | 0.23 | 1.09 (0.97–1.22) | 0.147 | ||
| After | 10.22 ± 3.61 | 9.66 ± 3.15 | 0.464 | 1.07 (0.91–1.26) | 0.413 | ||
| ANC (1000/μL) | <0.001 | 0.001 | |||||
| Before | 52.11 ± 13.69 | 51.42 ± 11.14 | 0.846 | 1.00 (0.96–1.05) | 0.831 | ||
| After | 24.27 ± 8.75 | 21.79 ± 9.69 | 0.116 | 1.06 (0.99–1.13) | 0.121 | ||
| RBC (million/μL) | 0.005 | 0.083 | |||||
| Before | 3.76 ± 0.55 | 3.55 ± 0.65 | 0.175 | 1.98 (0.67–5.80) | 0.214 | ||
| After | 3.69 ± 0.45 | 3.43 ± 0.55 | 0.049 | 3.63 (0.919–14.347) | 0.066 | ||
| Hb (g/dL) | <0.001 | 0.04 | |||||
| Before | 10.54 ± 1.20 | 10.22 ± 1.47 | 0.339 | 1.23 (0.77–1.97) | 0.388 | ||
| After | 10.18 ± 0.96 | 9.73 ± 0.77 | 0.079 | 1.78 (0.90–3.53) | 0.1 | ||
| MCV (fL) | <0.001 | <0.001 | |||||
| Before | 85.37 ± 7.05 | 87.72 ± 7.79 | 0.229 | 0.96 (0.88–1.03) | 0.253 | ||
| After | 82.59 ± 6.28 | 85.58 ± 7.39 | 0.101 | 0.93 (0.84–1.02) | 0.114 | ||
| CRP (mg/L) | <0.001 | 0.001 | |||||
| Before | 42.14 ± 39.79 | 44.25 ± 46.09 | 0.85 | 1.00 (0.99–1.01) | 0.797 | ||
| After | 13.31 ± 15.99 | 9.72 ± 13.41 | 0.408 | 1.02 (0.97–1.07) | 0.418 | ||
| Procalcitonin (ng/mL) | 0.996 | 0.961 | |||||
| Before | 2.11 ± 5.36 | 1.03 ± 1.31 | 0.496 | 1.08 (0.87–1.34) | 0.5 | ||
| After | 3.02 ± 11.70 | 1.61 ± 2.89 | 0.815 | 1.02 (0.88–1.18) | 0.804 | ||
| Fe (ng/mL) | 23.41 ±7.86 | 34.00 ± 15.12 | 0.257 | 0.89 (0.79–1.00) | 0.068 | ||
| Ferritin (ng/mL) | 142.86 ± 67.96 | 289.23 ± 163.70 | 0.171 | 0.99 (0.97–0.99) | 0.032 | ||
| TIBC (ug/dL) | 287.18 ± 36.23 | 335.25 ± 75.66 | 0.295 | 0.98 (0.95–1.00) | 0.078 | ||
| Hepcidin (ng/mL) | 0.839 | 0.616 | |||||
| Before | 242.26 ± 43.34 | 219.5 ± 23.33 | 0.492 | 1.02 (0.97–1.06) | 0.463 | ||
| After | 248.14 ± 54.80 | 212.40 ± 37.90 | 0.403 | 1.02 (0.98–1.06) | 0.377 | ||
| Urinary laboratory | |||||||
| WBC (/μL) | 333.21 ± 180.24 | 235.65 ± 208.50 | 0.055 | 1.00 (1.00–1.00) | 0.065 | ||
| RBC (/μL) | 103.11 ± 156.74 | 19.41 ± 27.17 | <0.001 | 1.02 (0.997–1.036) | 0.09 | ||
| Creatinine (mg/dL) | 0.838 | 0.493 | |||||
| Before | 11.15 ± 8.69 | 10.52 ±5.10 | 0.89 | 1.01 (0.88–1.16) | 0.884 | ||
| After | 10.90 ± 6.12 | 15.68 ±11.25 | 0.215 | 0.92 (0.80–1.05) | 0.224 | ||
| Hepcidin/Creatinine | 0.03 | 0.102 | |||||
| Before | 11.17 ± 7.20 | 10.42 ± 5.89 | 0.847 | 1.02 (0.86–1.20) | 0.84 | ||
| After | 7.84 ± 4.66 | 5.46 ± 1.72 | 0.329 | 1.17 (0.86–1.61) | 0.322 | ||
All variables were analyzed by Student’s t-test between E. coli urinary tract infection (UTI) and non-E. coli UTI groups, expressed as p value. Data before and after 3 days of antibiotic treatment were analyzed by paired t-test and expressed as * p value. The relationship of each variable with E. coli UTI was analyzed by univariate logistic regression, expressed as odds ratio (OR) with 95% confidence interval (CI) and p value. All data are presented as mean ± standard deviation. ANC: absolute neutrophil count, C.I.: confidence interval, CRP: C-reactive protein, Hb: hemoglobin, MCV: mean cell volume, OR: odds ratio. RBC: red blood cell, TIBC: total iron binding capacity, UTI: urinary tract infection, WBC: white blood cell.