Table 5.

Cells present in peri-implantitis tissues and their functions.

Cells Type	Function and Disfunction
Epithelial cells	Apical proliferation, γ-H2AX, iNOS, NOX2, MPO expression
Fibroblasts	Lowered collagen production, mainly type I and III
Macrophages	Tissue infiltration, cytokine production, phagocytosis
Neutrophyls	Tissue infiltration, cytokine production, NETosis, ROS production
Osteocytes	Bone matrix production reduction, inability to repair the damages
Osteoclasts	Bone destruction, influence the bone metabolism
Plasma cells	Maintaining inflammation process, humoral immunity
T-type lymphocytes	Maintaining inflammation process, cellular immunity
Dendritic cells	Inflammation modulation, affect Langerhans cells response