Table 4.
Parameter | Neofax | ANMF | DPF | NNF | Pediatric and Neonatal Lexi-Drugs | BNF for Children |
---|---|---|---|---|---|---|
Dosing recommendations are differentiated by indication? | Yes | Yes | Yes | Yes | Yes, every dosing recommendation is associated with indication(s) | Yes |
Renal dosage adjustment (if applicable) | Yes, under the ‘Dose’ section | Yes, since 2020 | Yes, specific section, including advice on adjustment based on AKI for > 3 months of age. Dose adjustment for neonatal maturation included in neonatal dosing recommendation. | Yes | Yes, under the ‘Dosing: Neonatal’ section | Yes |
Hepatic dosage adjustment (if applicable) | Yes, under the ‘Dose’ section | Yes, since 2020 | If applicable and available under ‘Warnings and Precautions’ section. | Yes | Yes, under the ‘Dosing: Neonatal’ section | Yes |
Other dosage adjustments (if applicable) | Yes, under the ‘Dose’ section (e.g., TH and ECMO) | Yes, since 2020 | If available from literature (TDM, ECMO, Hypothermia, obesity and pharmacogenetics). | Yes | Yes, under ‘Dosing: Neonatal’, as Notes at the top | Yes |
AKI = acute kidney Injury, TH = therapeutic hypothermia, ECMO = extracorporeal membrane oxygenation.