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. 2023 May 8;10(5):848. doi: 10.3390/children10050848

Table 4.

Content and organization comparison between neonatal formularies: Dosing recommendations.

Parameter Neofax ANMF DPF NNF Pediatric and Neonatal Lexi-Drugs BNF for Children
Dosing recommendations are differentiated by indication? Yes Yes Yes Yes Yes, every dosing recommendation is associated with indication(s) Yes
Renal dosage adjustment (if applicable) Yes, under the ‘Dose’ section Yes, since 2020 Yes, specific section, including advice on adjustment based on AKI for > 3 months of age. Dose adjustment for neonatal maturation included in neonatal dosing recommendation. Yes Yes, under the ‘Dosing: Neonatal’ section Yes
Hepatic dosage adjustment (if applicable) Yes, under the ‘Dose’ section Yes, since 2020 If applicable and available under ‘Warnings and Precautions’ section. Yes Yes, under the ‘Dosing: Neonatal’ section Yes
Other dosage adjustments (if applicable) Yes, under the ‘Dose’ section (e.g., TH and ECMO) Yes, since 2020 If available from literature (TDM, ECMO, Hypothermia, obesity and pharmacogenetics). Yes Yes, under ‘Dosing: Neonatal’, as Notes at the top Yes

AKI = acute kidney Injury, TH = therapeutic hypothermia, ECMO = extracorporeal membrane oxygenation.