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Involvement of PEMT in lipid synthesis. (A) Pathways involving PC and PEMT in lipid synthesis (reproduced with permission from [17]) (B) BODIPY staining (green) of neutral lipids in HCV-infected cells (NS5A positive, red) treated with 20 nM siRNA targeting PEMT or scrambled siRNA control. (C) Quantification of normalised fluorescent activity of BODIPY staining in HCV- infected cells treated with 20 nM siRNA targeting PEMT or scrambled RNA (** p < 0.01).
