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. 2023 May 14;24(10):8745. doi: 10.3390/ijms24108745

Table 1.

Relative signal intensities of interactions for the sera, depleted sera (DS), and IgG fraction of ADHD and control samples with 11 lectins (and their simplified sugar specificities) measured by the lectin-based glycoprotein microarray. Statistically significant differences (t-test, ** p < 0.01, * p < 0.05) between the ADHD and control groups are shown in bold.

Lectin SNA ConA RCA LCA AAL PHA-E PhoSL WGA MAL-II PHA-L MAL-I
Sugar Specificity α2-6 SA Man Gal, GalNAc Man (with Core Fuc) Fuc 2/3 Ant. Bisecting CNG Core Fuc GlcNAc, SA α2-3 SA 3/4 Ant CNG α2-3 SA
Relative signal intensity (%) Serum ADHD 40.95 24.01 17.36 3.59 5.54 ** 2.23 3.30 1.74 * 0.99 0.29 n.a.
Controls 41.52 24.14 16.89 3.55 4.73 ** 2.53 3.27 1.90 * 1.10 0.38 n.a.
Depleted serum ADHD 30.95 23.34 * 26.02 * 2.91 4.85 4.18 ** 1.34 4.85 1.09 ** 0.19 0.26
Controls 30.15 24.22 * 24.81 * 3.24 4.38 4.93 ** 1.31 5.08 1.34 ** 0.20 0.34
IgG ADHD 16.69 * 21.52 13.37 22.57 10.80 * 11.28 1.66 1.21 0.07 0.78 0.06
Controls 22.37 * 20.07 13.57 20.92 9.05 * 10.21 1.84 1.06 0.10 0.72 0.08

Ant—antennary; CNG—complex type N-glycans; Fuc—fucose; Gal—galactose; GalNAc—N-acetylgalactosamine; GlcNAc—N-acetylglucosamine; Man—mannose; SA—sialic acid; n.a.—value not available due to SNR < 3.