Pentose and Glucuronate Interconversions |
67.05 |
This pathway forms the basis of other critical pathways, such as the carbohydrate metabolic pathway. It is involved in the interconversion of monosaccharide pentose and glucuronate, the salts or esters of glucuronic acid. This pathway includes 28 different members, according to the KEGG database. The pentose and glucuronate interconversion pathways play a significant role in many biosynthetic processes. It can be said that aberrant pentose and glucuronate interconversions can lead to various diseases, such as familial tumoral calcinosis [62]. |
Aldosterone-regulated Sodium Reabsorption |
61.61 |
The epithelial sodium channelplays a significant role in cancer cell proliferation [63]. |
N-Glycan Biosynthesis |
45.59 |
Glycosylation induces significant functional changes in various glycoproteins, including cell surface receptors, adhesion molecules, etc. These changes confer unique characteristics and phenotypes associated with cancer cells [64]. |
P-53 Signaling Pathway |
31.23 |
Activated by various stresses, genotoxic damage, etc., the P-53 signaling pathway can arrest the growth of cancer cells. Therefore, it is suitable for cancer detection and feature extraction analysis from biological datasets [65]. |