Table 8.

KEGG pathways mapped to prostate cancer genes obtained from FRD.

KEGG Pathway Name	Fold Enrichment Score	Significance
Biosynthesis of Cofactors	24.50	The Biosynthesis of cofactors can disrupt natural cell proliferation by rewriting cellular signaling and reprogramming the metabolic pathways [66].
Tryptophan Metabolism	60.30	This pathway is responsible for the aging process. It produces metabolites responsible for controlling inflammation, regulating energy homeostasis, and modulating behavior [67]. The tryptophan pathway promotes the intrinsic malignant properties of tumor cells, and at the same time, also restricts anti-tumor immunity. Thus, it has been targeted for drug design to produce efficient defense against tumor cell replication [68].