Table 2.

Correlations between mRNA expression of MITF and pigmentation genes in 64 UM patients from the Leiden cohort (microarray). Spearman’s correlation. MITF expression (Mean, ± SD) = 10.46 (±0.5). mRNA expression was determined in an Illumina microarray. Significant p values are shown in bold. MC1R = melanocortin 1 receptor; MLANA = Melan-A; PMEL = premelanosome protein; TYR = tyrosinase; TYRP1 = tyrosinase related protein 1; OA1 = ocular albinism type 1.

	Mean (±SD)	Correlation Coeff.	Sig (2-Tailed)
MC1R	7.95 (±0.6)	−0.406	0.001
MLANA	13.73 (±0.4)	−0.259	0.038
PMEL	14.38 (±0.4)	−0.123	0.33
TYR	12.08 (±0.6)	0.182	0.15
TYRP1	13.66 (±0.9)	−0.379	0.002
RAB 27a pr1	8.56 (±0.5)	−0.116	0.36
RAB 27a pr3	7.95 (±0.5)	0.332	0.007
OA1	9.84 (±0.6)	−0.106	0.41