Summary of findings 3. NPWT compared with the Healthpoint system.

Population: adults with pressure ulcers Setting: hospitals Intervention: NPWT  Comparison: Health point system
Outcomes	Anticipated absolute effects* (95% CI)		Relative effect (95% CI)	Number of participants (studies)	Certainty of the evidence (GRADE)	Comments
	Risk with NPWT (plus standard care)	Risk with NPWT (plus standard care)
The proportion of pressure ulcers healed	See comments	See comments		28 (1 RCT)		Participants with multiple wounds in the trial with data being reported at the wound rather than participant level, but the included study did not clearly report the number of participants randomised to each group. Data were not analysed further due to these units of analysis issues
Time to complete wound healing	This outcome was not reported for this comparison.
Adverse events	This outcome was not reported for this comparison.

CI: Confidence interval; NPWT: negative pressure wound therapy; RCT: randomised controlled trial

GRADE Working Group grades of evidence
High certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of the effect.