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. 2023 May 17;10(5):220. doi: 10.3390/jcdd10050220

Table 1.

Overview of most used PET tracers in functional cardiovascular imaging.

Tracer Name Function
H2[15O] H215O-water Myocardial blood flow quantification (gold standard) [5]
82Rb Rubidium-82 Myocardial blood flow quantification [6]
[13N]H3 13N-Ammonia Myocardial blood flow quantification [7,8,9,10]
[18F]Flurpiridaz 18F-Flurpiridaz Myocardial blood flow quantification [11]
[11C]Acetate Carbon-11 labeled acetate Myocardial blood flow quantification, myocardial oxygen consumption, and cardiac efficiency [12,13,14,15]
[68Ga]FAPI (i.e., FAPI-04, FAPI-46, etc.) Gallium-68 labeled fibroblast activation protein inhibitor Detection of fibrosis through targeting activated fibroblast response [16,17,18,19]
[18F]AlF-NOTA-FAPI-04 Aluminum-[18F]Fluoride labeled fibroblast activation protein inhibitor-04 chelated with NOTA
[11C]HED Carbon-11 labeled hydroxyephedrine Global and regional sympathetic innervation quantification [20,21]
[18F]FDG Fluorine-18 labeled fluorodeoxyglucose Evaluation of increased metabolism (e.g., inflammation) [2,22,23,24] and myocardial viability